Boiler plant operator salary


2021.06.11 12:31 serey23 StationaryEngineers

A stationary engineer is an operator of boilers, steam turbines, auxiliary equipment (ie. air compressors/pumps) or refrigeration machinery. He or she works in factories, offices, hospitals, warehouses or any other locations requiring the use that equipment. A stationary engineer has various titles. For example, boiler operator, power plant operator and/or watch engineer. In addition, they have various designations (first class, second class and third class). Anyone who is in the field regardles

2023.06.09 06:44 blissiictrl Valving and balancing liquids

Is it just me or does it feel like liquid balancing is somewhat broken? I have just finished building a 75GW nuclear plant which recycles waste for plutonium fuel, then sinks the plut rods (I know it's a waste but there's no waste stream!). I keep hitting snags with liquid lines, especially on out-feed and I feel like valves don't seem to work entirely as expected.
I come from a process engineering background (mechanical process designer) and I usually operate check valves after a pump or as a directional controller if I don't want backflow but when I built my nuclear plant I was having issues where alumina solution wasn't flowing out to the scrap refineries properly, and similarly with the heavy oil residue refineries it didn't seem to balance out well unless I threw a mk1 pump after each balancing junction.
Any tips or insights here?
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2023.06.09 06:42 raesyktoast No sissy six man’s with 17 operator kills

No sissy six man’s with 17 operator kills
Me and my friends have vowed to boycott sissy six man’s on Ashika. This gameplay video shows what happens when you do that. We got 17 operator kills by defending our place on power plant. We got swarmed by teams left and right the entire match. Please watch and let me know what you guys think of my teams gameplay here.
submitted by raesyktoast to DMZ [link] [comments]

2023.06.09 06:13 TeddyGoodman This is 60 cents more than a living wage in the city this job is posted.

This is 60 cents more than a living wage in the city this job is posted.
I could make more just driving a forklift in a warehouse or bartending 3 times a week.
submitted by TeddyGoodman to TheBrewery [link] [comments]

2023.06.09 05:27 duckingman Full Stack Accountant

Now that most tech sector are desperately trying to stay alive, I've seen more and more people putting "full stack" in their job title. Full Stack Developer, Full Stack Digital Marketer, Full Stack HR. It's inevitable same trend will befall accountants.

Accounting job posting in 2030.
Full Stack Accountant required, will be responsible for:
  1. A/P and A/R
  2. Tax entry and reporting
  3. Cash flow forecasting
  4. Monthly financial reporting
  5. Strategic management accounting (ad hoc)
  6. Operational costing analysis
Salary: 20% higher than minimum wage.
submitted by duckingman to Accounting [link] [comments]

2023.06.09 05:24 calmthanever The Very Best Vendors That Sell Asphalt Plant In Indonesia

The Very Best Vendors That Sell Asphalt Plant In Indonesia
Asphalt plants are sold by vendors worldwide. If you're in the market for equipment such as this, and you're trying to spend less, you really should try buying coming from a vendor operating out of Indonesia. If you discover the ideal vendors that sell asphalt plant in Indonesia, you'll be capable of cut costs while still purchasing a high-quality product.

Know What You Would Like

One of many criteria you'll wish to evaluate vendors on is the selection that they can offer. Make sure the vendor offers a variety of options that be right for you. For example, if you're trying to find a fully automatic asphalt plant, you should get a vendor that sells many asphalt plant business for sale that fall under this category.

Together with having clearly defined expectations for the product that you're buying, you should have a precise picture of what you really are ready to spend. Find out if the owner can assist your finances. Make sure you won't buy something that you'll regret.

Be Aware Of Brands

You could be well-familiar with several of the top brands that manufacturer heavy machinery within your region. However, it's likely you are aware of far less about Indonesian manufacturers. Should you get to know highly respected brands, you'll have the ability to hunt for these brands as you may shop.

Which brands should you really be keeping a watchful eye out for? Aimix is a brand that a great many people know and trust, and Ammann has an excellent reputation as well. Invest some time researching brands to ensure you'll possess a better idea of what to anticipate from certain manufacturers.

Ask For Advice

Talk with a few of your colleagues in the market and find out if any one of them been employed by with Indonesian-based vendors previously. If they have, you must make them share their experiences with you. Determine whether there is a particular vendor that numerous professionals recommend. Check more info here:

Even though you aren't able to talk to someone personally, you can obtain a broad spectrum of opinions online. If you this, you'll have a better picture of the things various vendors are offering.

Look At The Small Print

You won't need to be caught off-guard when your gear is shipped over to you. To preclude this from happening, there are some specific things you will need to search for before you officially place an order.

Find out when the product you happen to be buying is included by any sort of warranty. Check to see what is and isn't included under that warranty. You should also learn more about the shipping process. What will you be shelling out for shipping? How long will shipping take? How will your equipment be protected because it is shipped? These are the basic form of questions you'll want in order to answer.

When your goal is to find the best vendors that sell asphalt plant in Indonesia, you'll would like to keep your advice above in mind. When you know where to start, buying from Indonesia can be a very positive experience.
submitted by calmthanever to u/calmthanever [link] [comments]

2023.06.09 05:05 OpaqueStain How do I start my data scientist journey?

I am 25 year old, working as a operations specialist with an average salary in Florida. I completed my bachelors of science in Finance in 2022. Given the current state of the world and where it’s leading to, I have decided to change the course of my career and to either go back to school for computer science, or learn data science on my own through coursera, youtube or linkedin learning. And then possibly pursue a masters in data science. I am so lost. I have no idea where to start from. 2017 i decided to do finance, because i didn’t know if this was the way the world would end up like. Can someone suggest me the best way to integrate myself a growing tech field. I consider finance knowledge to be a plus for me. Need serious guidance. Thank you!
submitted by OpaqueStain to datascience [link] [comments]

2023.06.09 04:58 AIMIXindonesia Unlocking the Potential of AMP Aspal Mixing Plant

Unlocking the Potential of AMP Aspal Mixing Plant
AMP Aspal Mixing Plants play a pivotal role in the construction industry, providing a reliable and efficient solution for asphalt production. This article aims to explore the various aspects of AMP Aspal Mixing Plants and uncover their untapped potential. By delving into their components, advantages, operation factors, advanced technologies, and sustainability benefits, we can unlock a new level of understanding and utilization for these plants.

Advantages of AMP Aspal Mixing Plants

AMP Aspal Mixing Plants offer several advantages over traditional asphalt mixing methods. One key advantage is the increased production capacity and efficiency they provide. With their advanced design and technology, these plants can produce a larger volume of high-quality asphalt mix in a shorter time frame. The enhanced control over mix quality is another significant advantage, as it allows for precise adjustments and consistency in the produced asphalt. Moreover, AMP Aspal Mixing Plants offer cost-effectiveness and sustainability benefits by optimizing resource usage and reducing waste.

Key Factors for Successful AMP Aspal Mixing Plant Operations

To unlock the full potential of AMP Aspal Mixing Plants, certain key factors need to be considered during their operations. Proper site selection and preparation are crucial to ensure smooth plant installation and operation. Calibration and regular maintenance of plant components, such as the burner, conveyor systems, and filters, are essential for optimal performance. Additionally, implementing robust quality control measures and testing procedures guarantees that the produced asphalt meets the required standards.

Advanced Technologies in AMP Aspal Mixing Plants

The potential of AMP Aspal Mixing Plants can be further unlocked through the integration of advanced technologies. Automation and computerized control systems enable precise monitoring and control of the asphalt mixing process. Data analytics and real-time monitoring provide valuable insights for optimizing plant performance and detecting any deviations. Innovations focused on energy efficiency and emissions control contribute to sustainable asphalt production while meeting environmental regulations.

Maximizing Productivity and Quality in AMP Aspal Mixing Plants

To harness the full potential of AMP Aspal Mixing Plants, maximizing productivity and maintaining quality are crucial. Optimal mix design and material selection play a significant role in achieving the desired asphalt properties. Efficient workflow management, including proper logistics planning and real-time communication, minimizes delays and maximizes productivity. Continuous training and skill development programs for plant operators ensure their competency in managing the complex operations effectively.

AMP Aspal Mixing Plants for Sustainable Asphalt Production

In today's environmentally conscious world, sustainable asphalt production is paramount. AMP Aspal Mixing Plants offer opportunities for sustainable practices. Reclaimed Asphalt Pavement (RAP) can be incorporated into new mixes, reducing waste and conserving resources. Strategies to minimize environmental impact, such as energy-efficient operations and emissions control, align with sustainability goals. Compliance with sustainability standards and regulations further promotes responsible asphalt production.

Overcoming Challenges in AMP Aspal Mixing Plant Operations

Unlocking the potential of AMP Aspal Mixing Plants involves addressing common challenges encountered during their operations. Equipment breakdowns and maintenance issues can impact productivity, emphasizing the importance of regular maintenance and troubleshooting. Weather conditions can also pose challenges, requiring proactive measures to mitigate their impact. Strategies to minimize production delays and downtime are essential for unlocking the full potential of these plants.


Unlocking the potential of AMP Aspal Mixing Plants requires a comprehensive understanding of their components, advantages, operation factors, advanced technologies, sustainability benefits, and challenges. By embracing the advancements in these plants, we can maximize their productivity, enhance asphalt quality, and promote sustainable practices. The opportunities presented by AMP Aspal Mixing Plants pave the way for a more efficient and environmentally friendly future in asphalt production. It is through this understanding and utilization that we truly unlock their full potential.
submitted by AIMIXindonesia to u/AIMIXindonesia [link] [comments]

2023.06.09 04:42 modern-machine glass bottle vodka filling machine,Liquor filling equipment,wine production line

vodka filling machine
Modern vodka filling machine is suitable for filling and sealing vodka, liquor and other alcoholic beverages. It has the characteristics of fast filling and sealing speed, stable machine operation, good sealing quality, beautiful appearance, convenient use and maintenance, touch screen operation, frequency conversion speed regulation, etc.

submitted by modern-machine to u/modern-machine [link] [comments]

2023.06.09 04:40 BrianC_ The Future of the NACL Business Model

The news release was pretty vague and poorly worded, so this is all just an educated guess for how they're planning to transition the NACL.
The two major changes are these --
A new NACL business model, in addition to the previously committed $300,000, that shares revenue between the tournament operator and participating teams to drive towards long-term sustainability
Improvements to the NACL governance model, including a Team Participating Agreement (TPA) and vetting process of the participating team organizations
The way this reads to me is that the organizations that wanted to leave the NACL are still free to leave the NACL. And, in the future, they'll also be free to come and go as long as they abide by the yet undisclosed TPA.
So, they're clearly transitioning to a more voluntary participation model.
In theory, this is better. Since, according to the first point, there will be revenue sharing with the tournament operator in the future, this means that the tournament operator, organizations, and players should all be on the same page in terms of the goal of the league. Their goal is not to just be a marketing expense for Riot or to help Riot sell more RP/skins/etc. Their goal is not to just sit on an investment with the hope that the value of their spot in the league will grow in value. Their goal should be to be an entertainment product that generates views, fans, and ultimately tournament / team sponsorships. Their sustainability now depends on that. It's much more similar to the ERLs.
Now, content matters. Performance matters. Player personalities matter. PR matters. Marketability matters. Like we saw with DSG, the tournament and teams are going to need to be creative again.
And, because that's all known up-front, the teams and players that ultimately opt to join the league will know what their business situation is. In the event that any team in the league isn't on board or isn't carrying their weight, the TPA means they can be removed.
Ultimately, if league still functions as a developmental league, it means a lot of these characteristics might also filter upwards into the LCS. Because the tournament organizer and teams have to more honestly generate money through views and fans rather than depend on VC support, the players that they develop will also have to fit that mold. So, if they eventually make it to the LCS, they might bring a long some of that marketability.
On top of this, if the new player contracts are longer, it's also possible that teams will have the option to make money through player buy-outs when LCS teams bring them up. So, from a player development PoV, developing players could now have a very strong financial incentive.
I don't know how the tournament operator agreed to this, but I guess Riot could've strong armed them into accepting their future reality.
The main issue I'm seeing is that it's a steep buy-in for no guaranteed return on investment. If they're going to a decentralized league as was suggested, that'll be much easier to stomach, but you'll still be on the hook for player salaries, coaching salaries, and potentially travel fees to live events. If it's still the same system, that's way too much money to pay. Player salaries, housing, coaches, etc. For that amount of money, it's just not a good investment and will instead be a passion project.
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2023.06.09 04:33 calmthanever Three Tips for Maximizing the Performance of a Jaw Crusher

Three Tips for Maximizing the Performance of a Jaw Crusher

When you're choosing a jaw crusher, you'll desire to take time to go with a durable and-quality product. You'll should also make certain you're getting excellent performance out of your equipment. If you want to enhance the performance of your own jaw crusher, these are some simple suggestions you can attempt.

Conduct A Simulation Prior To Starting Utilizing Your New Machinery

Don't start using your jaw crusher without conducting some type of analysis. You'll wish to have a clearer picture of how your jaw crusher is going to be used. Conducting a simulation will help you to spot potential issues before they happen. You'll have the ability to address issues and be sure that your primary jaw crusher plant works effectively.

There are numerous of tools and resources that can present you with useful theoretical data. You might need to purchase software that provides you with this kind of data. Although it boosts your spending, it's still a rewarding investment. Analyzing what you're likely to be doing ahead of time is a terrific way to avoid potentially costly mistakes.

Figure Out How Your Production Line Will Probably Be Operated

You'll possess a better knowledge about your jaw crusher and then any other machinery that's in your production line when you see how it's going to be operated in advance. Determine who is going to be dealing with your jaw crusher. Be sure they're properly trained and learn how the machine should really be used.

Once you know exactly how your production line is going to be operated, you'll be capable of develop a plan that can help you to increase efficiency. Whenever people are operating more proficiently, it's only natural that you'll visit a better performance through your jaw crusher. Properly training your workers can also help you to improve performance from your machine. Make certain that everyone which will be working together with the machine knows what's expected from their store. Check more info here:

Give Your Equipment The Maintenance It Needs

Even if you select a top-of-the-line jaw crusher, you will definitely have difficulties with your machinery should you don't provide it with the appropriate maintenance. Equipment this way needs to be maintained, and an absence of maintenance could cause numerous problems for you. Actually, without maintenance, your machinery can even end up breaking down.

Look at the manual that was included with your jaw crusher to help you see what type of maintenance it requires. Maintenance doesn't take considerable time, also it can dramatically boost the lifespan of your heavy machinery. Heavy devices are expensive, which is the reason you'll want to make sure your machinery remains in like-new condition. With regular maintenance, you can avoid performance problems whilst keeping your machine running perfectly.

If you've dedicated to a jaw crusher, you'll want to take steps to increase its performance. With all the care and some planning, you can find better performance from the heavy equipment. Be sure that you're getting the best possible performance from your jaw crusher philippines.
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2023.06.09 04:32 oooh___ahhh Help!

I saw this at the cash saver yesterday, and I’m wondering if anybody wants to meet up and discuss some options before the scoping.
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2023.06.09 04:29 Bubzoluck [30 min read] The Opioid Epidemic before the Opioid Epidemic - Exploring Morphine Derivatives and the First Opium War (Part 1)

[30 min read] The Opioid Epidemic before the Opioid Epidemic - Exploring Morphine Derivatives and the First Opium War (Part 1)
Hello and welcome back to SAR! I have written and rewritten this post a few times now and I think I have landed on a format I am happy with. When we talk about the impact of medicine on history its important to get the context right, and I think I have found a way to talk about our topic. So what is it? No chemical is more important to the world of medicine than Opium, okay maybe Penicillin, but today we will say its Opium. Principally an analgesic (anti-pain), the Opium Poppy allowed for humans to take away pain in great degrees and further development on the natural chemicals has opened up surgery and post-op recovery. While we tend to look at the recent Opioid Epidemic as the only issue regarding Opiates, history reveals to us a very similar precursor. Also please head over to u/jtjdp post about morphine derivatives here! She does an amazing job explaining the higher level concepts of medicinal chemistry that I just wouldn’t do justice. Alright, enough quibbling, let’s get to the good stuff.
Disclaimer: this post is not designed to be medical advice. It is merely a look at the chemistry of medications and their general effect on the body. Each person responds differently to therapy. Please talk to your doctor about starting, stopping, or changing medical treatment.

How Much do you Know About Pain?

To be alive is to feel pain, and emo sentiments aside, this is one of the biggest biological properties of the central nervous system. When you think about it, how does the body take external stimuli and allow you to recognize it? The answer is the sensory nervous system which is responsible for sensing many different types of stimuli: temperature, pressure, pain, and chemicals. These sensory neurons carry the information from the extremities and transmit it up the spinal cord into the brain for processing. From there the brain alerts you to the issue allowing you to correct whatever problem is causing the pain. Let’s take a look:
  • We call these receptors Nociceptors and activation of these neurons in the periphery leads to a signal being sent towards the spinal cord. Those peripheral nerves eventually complex with the Dorsal Horn of the spinal cord and interface with the central nervous system to transfer the pain signal. This signal is then sent Ascending to the Thalamus where the pain signal is recognized and initiates a response (such as pulling your hand away from the hot stove). But that’s not the full story, the brain also sends signals back down Descending to modify the incoming signal and dampen it. Its this modifying that makes pain fade over time when you aren’t focusing on it—otherwise the brain would be overwhelmed by the repetitive signal and continuously think injury is still happening. Now let’s divide this process into its two parts, first up the Ascending pathway.
  • As the Action Potential travels from the periphery towards the Spine it causes the influx of Calcium into the Presynaptic Neuron. This neuron is what carries the original signal to then transfer into the Spine for further traveling. Eventually we reach the Synapse where the finger-nerve and spine meet and we get the transfer of information via Neurotransmitters. In this case, two chemicals are released: Glutamate and Substance P (which literally stands for Substance Pain). Glutamate will activate two receptors (AMPA and NMDA) which are Excitatory and stimulate the continuation of the pain signal up to the brain. Substance P activates the NK1 receptor which enhances the frequency of the pain signal (the throbbing) and the intensity of the pain burst. So to simplify, Glutamate allows the signal to be passed up to the brain but depending on the strength of the original pain signal more or less Substance P is released which modulates the strength and attention-grabbing nature of it. Okay great, we sent the pain pathway up and it will get processed in multiple different parts of the brain. But the brain can’t have that signal stinging it so it must send information back down to dampen that pain signal. This is where that aforementioned Descending pathway comes in. Above you can see how the blue line reaches down out of the brain and back into the spine to turn ‘off’ the signal. This is the basis of Analgesia or pain relief.
  • Okay so now we have to divide the action of the Descending pathway which acts to dampen and modulate the original signal coming into the brain. Now, normally at rest this Descending neuron is inhibited so any fresh incoming signal is not inhibited from the get go but once that pain signal does come in, we get the good stuff! In response to pain the brain releases substances called Endorphins which activate the mu Opioid Receptor (MOR) located on the Descending pathway. Now MOR are inhibitory in nature so they are inhibiting the inhibitory resting state of neurons, or in other words, are allowing the Descending neuron to activate. And this is an important fact to recognize, Opiates do not inhibit pain, they inhibit the physiology of the nervous system that prevents modulation of the pain signal.
    • Once the inhibition is inhibited, the Descending neuron is free to release two neurotransmitters onto the nerve that was carrying the original pain signal. Both Norepinephrine and Serotonin are released to activate their respective receptors which inhibit the release of Substance P and Glutamate thus decreasing the incoming pain signal. Likewise MOR receptors are found directly on the incoming nerve and further prevent the release of Glutamate and Substance P as well as being found on the Ascending neuron preventing the activation of the NMDA/AMPA and NK1 receptors. The result: dampened incoming signal and decreased pain sense being sent to the brain.

The Stars Align in the Shape of a Poppy
To start our story about Opiates we need to turn to the great precursor—Opium. Opium itself is not a chemical but rather a really thick liquor (called latex) that contains a high concentration of Morphine (and some Codeine). There are 38 species of Poppy plants but only two produce Opium is great enough supply that it is worth farming them and humans have been cultivating these varieties for as long as we have known about the plants. When humans settled into Mesopotamia (near modern day Iraq), Poppies were one of the few plants grown in plots as large grain or vegetable fields (meaning that they were thought of as valuable as food). Throughout the Greek age of medicine (pre-500 BCE) through the Islamic medicinal revolution (500 BC-1500 AD), Opium was a major component of treatment, assisted suicide, and poison. In fact its through the rise of the Muslim Caliphates that we see the export of Opium to other parts of the world, especially through the Mediterranean Sea once the Crusaders return. Opium trading to the East via the silk roads was an almost continuous affair since time immemorial and Pakistan was a major growing area for the Eastern Poppy trade.
  • By the time after the Crusades (11-13th centuries), we start to see the West’s fixation on Opium. For many reasons Europe didn’t develop many psychoactive plants to the same degree as more humid/hot climates like Africa, the Middle East, and India. This is why the importation of Opium (and also Marijuana) was such a trade commodity and staple in the development of Western medicine. During the Renaissance and the revival of Greek philosophy we start to see the re-fascination with Opium and by the 1600s we see merchants importing Laudanum into Europe for recreational and medicinal use. The standard use of Tincture of Opium (which is Opium dissolved in ethanol, a DEADLY combination) was a particularly favorite preparation which was prescribed to the lowest day-worker all the way up to kings.
    • The importation and use of Opium exploded in the late 1700s once the British conquered a major Poppy growing region of India. This region (western India and most of Pakistan) was originally slated to grow cotton like the American colonies but the region wasn’t wet enough to sustain the plant—it could however grow copious fields of Poppy plants to create Opium. Throughout the 18th century the British Raj became the largest exporter of Opium to Europe and after the discovery that Mercury and Arsenic may not be safe, Opium took over their duties. By 1780 almost all major remedies incorporated the use of Opium in some capacity and with the huge supply, it was incredibly cheap.
  • Poppy wasn’t only important to the British for its medicinal properties but also to bolster the huge amount of loss they were incurring in global trade to one trade partner—China. After she made contact with China in the mid-1500s, Britain starting to import HUGE amounts of tea as the Brits became literally addicted to the substance. By 1800 a full 15% of the ENTIRE British Empire’s revenue was being spent on importing tea, that’s 30 million pounds per YEAR, leading to a massive trade deficit. This means that more money was being sent to China literally enriching a foreign country while the British public was getting their fix on the black stuff. Oh and just in case you think things haven’t changed, Britain still accounts for 42.6% of the world’s tea consumption—seriously Brits, ever heard of coffee? Anyways, all this money leaving the British economy to be spent on non-Empire sustaining commodities was a major national security risk for the British. It would be different if they were importing gunpowder like the Dutch were or Silver as the Spanish had but literally they were consuming the riches they were spending the money on.
    • Remember too that the British were not in the best position by the turn of the 19th century—they had just lost their colonies in the Americas, involvement in the Napoleonic Wars killed a generation of men, and the push to develop industries over public health led to a focus on fast growth rather than smart growth. One of the results of the Napoleonic Wars was the British occupation of the Island of Java which developed a very potent Opium which was traded with Chinese merchants regularly. Soon British merchants realized they could rebalance the trade deficit by selling Javanese Opium into China but the small island was unable to produce enough Poppies to meet the demand. So Britain turned to another one of its colonies, India.
  • India by the end of the 1700s was a bit of a challenge. The British hold on the subcontinent was firm but they couldn’t grow the cash crops they wanted. Indian cotton was nothing compared to Egyptian or Southern American (i.e. Virginia/North Carolina/Georgia) cotton and the Indian tobacco was known for being bitter. But by the 1770s the British government realized that Poppy was an easy crop to grow and the demand across the border with China was an easy market; British traders brought their cargo to small islands off the coast of China where it was sold for silver. Initially the Chinese didn’t mind the sale of Opium in their territory—when the British traders collected the silver from the sale they would almost immediately use it to buy Chinese goods, thus driving tax revenue for the Chinese government.
  • But if you buy Opium, people are going to use that Opium. By the 1810s all trade with foreigners was restricted to just one port, Canton, and slowly the city started to develop a habit for the drug. The use of mind altering substances was curtailed pretty quickly for hundreds of years in China—the Ming Dynasty banned tobacco in 1640 and the Qing banned Madak (a powdered Opium containing tobacco) was similarly banned in 1729. But by 1790 more and more Chinese citizens were becoming addicted to the substance; what started as a recreational drug slowly became a crippling addiction that took hold over Canton. For a rigid society, the crippling Opiate addiction was a moral corruption for the Qing government and forced them to curtail Opium importation in 1780 and then an outright ban in 1796.
  • Knowing just how devastating the Opium was having on the inhabitants of Canton, as well as how it spread further inland, British merchants kept peddling their drug. Older ships with larger hulls were converted into floating warehouses and parked just outside of navigable waters. Once set up, Opium smugglers would pull up, purchase the Opium and avoid any oversight by the Chinese government to prevent the sale of the drug. Following their mother country, American merchants started to sell Turkish Opium, an inferior variety, at a much cheaper rate leading to drug peddling competition with more and more tons of Opium being sent into China. This drove down the price of Opium considerably which ultimately increased the demand.
    • This demand eventually led to reversal of trade, meaning that more silver was leaving China to pay for Opium than the British were using to pay for Chinese goods. American and European traders could show up in Canton with holds full of Opium, sell it off for a profit, and then make a tidy silver profit to bring back to Europe. Likewise the importation of cheap machine-made cotton, furs, clocks, and steel into China driving down domestic profits.

Let’s Look at the Drugs a Bit
Stepping away from the history a bit, let’s introduce the Family. Okay so we understand how pain is sent to the brain and how it modulates but there is so much more to the mu Opioid Receptor and that’s not the only kind of Opioid receptor that we have. The two most clinically useful receptors are the Mu and Kappa Opioid Receptors (KOR) because they result in analgesia but there is a Delta Opioid Receptor (DOR) that is worth mentioning. The majority of the Opiates that we know and love are Mu agonists but there are some very interesting Kappa agonists that are worth mentioning as well.
  • Above is a chart that shows the binding affinities of select Opiates to the Mu receptor. The smaller the number is, the more tightly they bond. Now affinity is different than potency—potency is a measure of how much drug (in g) is required to produce the same effect. So even though morphine has a higher affinity than fentanyl, fentanyl has a MUCH more potent effect (which is why it can be so dangerous, you only need a little). Now many of the opiates cause the same effect so I want to spend more time on what makes them all so different:
  • First up we have the 5-Ring Morphinians which are derived from the natural product Morphine. These structures have 5 component parts: an aromatic benzene ring (A), a completely saturated bridge ring (B), a partially unsaturated ring with an alcohol attachment (C), a piperidine heterocycle above the rest of the structure (D) and finally a ether linkage between the top and bottom of the structure to keep it fairly rigid (E). Truthfully we are only going to focus on two locations—firstly the top alcohol (red circle) can be methylated to form Codeine, a natural Prodrug of Morphine. A Prodrug is one that is biologically inactive but goes through an initial metabolism once ingested that makes it active.
  • In fact it’s this initial metabolism of Codeine that makes it very interesting. In order for Codeine to exert any pain relief it needs to be converted to Morphine which actually exerts the desirable properties. This is done by the liver enzyme CYP2D6 which is a pretty minor pathway for Codeine—only about 10% of the Codeine is actually converted to Morphine to have some action. Because of this 2D6 dependent pathway we have to be careful about administering drugs that might inhibit the 2D6 pathway because that would mean we are preventing codeine from being active. Drugs like Fluoxetine (Prozac) and Paroxetine (Paxil) are strong 2D6 inhibitors and so if we administered Codeine to someone taking this drug they’d never get any benefit from the Codeine. In addition there are genetic/ethnic differences that pharmacists can account for such as 2D6 activity. If you are someone with very little 2D6 activity then you would also not convert Codeine to Morphine and thus get no action from the drug—this may be a reason why some people say Codeine doesn’t work for them. Another reason could be that they are Rapid Metabolizers and quickly convert the Codeine to Morphine and thus get a massive hit quickly after ingestion—in that cause you’d need a much smaller dose than another person for the same effect.
  • A different drug that is the opposite of Codeine is Hydromorphone (Dilaudid) which has a Ketone on ring C. This ketone and the lack of the double bond on this ring increases the lipophilicity of the drug and increases its ability to penetrate into the brain and thus have a greater effect. In fact Hydromorphone is 5-10x more potent than Morphine due to its greater ability to penetrate into the brain and increased receptor affinity for the mu receptor. Because the A ring OH is not capped with a methyl group, we don’t need to rely on 2D6 to metabolize Hydromorphone into an active drug form which again increases the activity of this drug compared to Codeine.
  • So combine these two structural changes—the capped OH on ring A as seen in Codeine and the increased affinity found with the ketone in Hydromorphone and we get Hydrocodone (Norco, Lorcet). Well in this case you’d get a drug that has very good affinity for the mu receptor (better than codeine) BUT is still reliant on the small 2D6 pathway for activation (worse than morphine). In this regard only about 10% of Hydrocodone is active at a time. We can see this effect in the relative doses for equivalent effect: to match the effect of 30mg of Morphine, we’d need only 7.5mg of Hydromorphone (more active) but need 200mg of Codeine (less active).
  • This brings us to our last drug of this class, Oxycodone which has a special OH group found on Ring B. What you’ll notice is that Oxycodone has that capped OH on ring A so it requires metabolism through 2D6 just like Codeine and Hydrocodone. When it is uncapped it becomes Oxymorphone which has 3 times as much effect as Morphine BUT that extra OH makes Oxycodone an exclusive Mu receptor agonist. Unlike the other drugs which may go to other receptors causing side effects (more on this later).
  • Next up I want to look at some Mu opioid receptor Antagonists or those than inhibit the function of the opioid receptor. Looking at the first two drugs, Naloxone and Naltrexone, we can see that they have the structure similar to Hydromorphone so they would have incredible brain penetration and affinity for opioid receptors BUT they contain that funky Nitrogen tail. Now normally there is a short methyl tail that is required for the function of Morphine but by adding a bulkier tail the drug is able to fit inside the receptor but prevent activation. What’s most important about these two drugs is that they have much more affinity for the receptor than other opiates. We can see this effect in the graph above: when no Naloxone is present, Fentanyl occupies the opiate receptor about 75% of the time. But as soon as Naloxone is administered that number drops swiftly (within minutes)--this is because Naloxone has a higher affinity for sitting in the receptor than Fentanyl. Think of it like the bully Naloxone coming up and pushing the poor defenseless Fentanyl off the swings so the bully can play on it (except in this instance Fentanyl is causing an overdose and we need to save someone’s life).
  • Buprenorphine is similar but it is a Partial Agonist instead of being a full antagonist. Buprenorphine is not a 5-ring Morphinian byt a 6-ring Oripavine that has a few different modifications. The biggest additions is that it has the bulky Nitrogen tail found in full Antagonists but it has this funky C ring tail which fights the antagonism. The result is a tug of war between the antagonism of the Nitrogen tail and the agonism of this new C-ring tail resulting in Partial agonism—so if you took Buprenorphine you’d notice a markedly decreased pain relieving ability but importantly there is a ceiling effect, its much harder to overdose on Buprenorphine than other full agonists. In addition in the second graph we can see that Buprenorphine has the greatest affinity for the receptor than our other agonists which prevents someone from taking a more potent opiate while taking Buprenorphine. In this case the bully is already sitting on the swing and scaring away the other kids thus preventing them from having a turn (and potentially causing an overdose). This does mean that if someone was taking a more potent drug (like Fentanyl) and then took Buprenorphine, it would cause withdrawal just like Naloxone or Naltrexone.
  • Speaking of withdrawal, let’s take a look at how that happens. Remember that the pain signal is caused by the activation of AMPA and NMDA receptors from the peripheral nerve. AMPA is a type of receptor called a G-Protein Coupled Receptor or GPCR which in this case is linked to an Excitatory G-protein which leads to the activation of the nerve. When AMPA is activated, the G-protein (Ga) activates an enzyme called Adenylate Cyclase (AC) which increases the production of pro-activity cAMP—or in simpler terms—when AMPA is activated, it leads to an increase in levels of pro-pain molecule cAMP. The Opioid receptor is also a GPCR but it is linked to an inhibitory G-protein which prevents the action of Adenylate Cyclase and thus leads to a decrease in cAMP levels. So Opiates prevent pro-pain cAMP signaling from continuing.
    • In the second graph we can see how tolerance forms. Initially (A), Adenylate Cyclase and cAMP levels are not affected by having opiates even though their ability to push along the pain signal is blocked. After a few hours, the leftover cAMP is degraded and cAMP levels start to drop significantly (B). In response to these levels going down, the activity of Adenylate Cyclase starts to increase and increase (C) which raises the level of cAMP. This rise in Adenylate Cyclase activity opposes the action of the opiate which necessitates the need for increased doses of Opiates and is why tolerance forms. As sustained inhibition of Adenylate Cyclase continues, the body upregulates Adenylate Cyclase activity to create more cAMP and to combat this we increase the dose.
    • Now what if after years of taking an Opiate we suddenly administer Naloxone, an Opiate antagonist. Well after weeks to months of taking an Opiate, the level of Adenylate Cyclase activity is WAY above baseline. When you administer the antagonist, suddenly Adenylate Cyclase is able to produce a TON of cAMP that normally is blocked which leads to a MASSIVE amount of downstream signaling. The result is intense nausea and vomiting, stomach cramps, fever, anxiety, insomnia, and cravings. Thankfully the withdrawal process ends after about 72 hours but is one of the worst experiences someone can go through which is why proper down-tapering of Opiates is extremely important.

A Change in Trade Policy
Oh, you’re still here. Neat! So by the 1820s the Qing dynasty was running into many problems regarding Opium. Firstly they needed the Opium taxes to fund their efforts to put down the White Lotus Rebellion and retain power. But after almost 30 years of trade the effects on Chinese communities could not be ignored along with local officials operating under the imperial trade department, the Hong, profiting from bribes to allow Opium. Regardless of initial efforts things were getting out of hand for the Qing government. In 1800, about 4000 chests of Opium or 560,000 pounds entered the country but by 1830 that number exploded to 20,000 chests or about 3 million pounds. But more than the amount of Opium actually entering the country was the incessant rudeness of the British government to open trade.
  • One of the “problems” for the British traders was how clamped down trade was with China. By 1800 all trade was limited to just Canton and the Hong was a strict master of trade. Foreigners were not allowed to appeal decisions made by the Hong and only Chinese traders could sell goods further inland than Canton. Traders chafed against this extreme oversight and sent hundreds of letters to the Hong requesting special dispensations which were summarily denied. Things changed significantly in 1834 when the Chinese trade was de-monopolized away from the East India Company allowing any private trader to get involved in the Eastern trade.
  • In August of 1834, the British sent Lord William John Napier to Macau as superintendent of Chinese trade with the explicit order to follow all Chinese regulations. Thinking he knows best, Napier decided that the restrictive Chinese trade system was too restrictive and sent a letter to the Viceroy of Canton. This was unheard of—NO foreign traders were allowed to speak directly with Chinese officials and the Viceroy refused to accept it. So why not double down by ordering two British ships to BOMBARD two Pearl River forts as a show of force? Luckily Napier died of Typhus almost directly after else it would have resulted in a full blown war.
  • In 1839 the Qing government appointed Lin Zexu as the Opium czar to completely eradicate the Opium trade from China. Lin banned the sale of Opium in China completely, set up rehabilitation centers for those affected by the drug, and put addicts to work to distract them while detoxing. Lin demanded that all Opium supplies must be surrendered to Qing authorities and any Chinese citizen disobeying the order would be punishable by death. He even went as far as closing the Pearl River Channel, trapping British traders in Canton and seizing their Opium warehouse stockpiles.
  • The replacement for Napier was Admiral Sir Charles Elliot who protested the seizure of the Opium stockpile but knew that they could do nothing. He ordered all Opium ships to flee and prepare for battle which caused Lin Zexu to beseige a group of traders inside a Canton warehouse. Elliot convinced the traders to cooperate with the Chinese government and surrender their stock, saying that the British government would compensate for the lost Opium (which he had no authority to do). During April and May 1839 the British (and American) traders to surrender 20,000 chests of Opium which was burned for three days outside Canton. Following the burning, trade resumed to normal except no more Opium was allowed. Like many other instances of the government removing legitimate sale of a drug, the black market increased markedly.
  • In July 1839 a new scandal rocked the British-Chinese trade system; two British sailors became drunk and beat a man death outside of his village. In response, Superintendent Elliot arrested the two men and paid compensation to the villager’s family for the loss of the man but Elliot refused to hand over the sailors to the Qing government. Lin Zexu saw this as a blatant disregard for Chinese law—afterall traders needed to understand that they can’t just come to China and violate Chinese law as they saw fit. Elliot offered to hold a trial on a British ship in front of Chinese officials to show that the men would not get off free. This incident would start the smoldering.
    • On September 4th, Elliot sent two ships to Kowloon to buy food and provisions from Chinese peasants. While approaching the harbor, three Chinese war junks gave permission to the two British ships to trade but that permission was rescinded by the commander of Kowloon fort. Elliot fumed against the slight and said that if the British were not allowed to trade by 3pm, he would fire on the fort. 3pm passed and the British opened fire on the fort causing the Chinese junks to return fire. The fighting continued for 7 hours until nightfall and Elliot had to prevent the British officers from pressing the attack, thus ending the Battle of Kowloon. Having driven off the Chinese ships, the British purchased the supplies they needed while the Kowloon commander claimed that both ships were sunk and 50 British sailors killed.
    • The reaction in Britain was about as much as you expect. Prime Minister Palmerston sent out letters to the Governor General of India to prepare marines to invade China and another letter to the Chinese Emperor telling him that Britain would send a military force. He sent a letter to Superintendent Elliot to set up a blockade on the Pearl River and capture Chusan Island. He also instructed Elliot to accomplish the following objectives:
      • Demand the respect as a British envoy from the Qing Government.
      • Secure the right for British law to be doled out on British subjects
      • Get recompense for destroyed British property, especially the illegal drugs that they destroyed
      • And most important, End the Canton System thus opening up China to free trade for the first time, ever.
Alright this is where we will leave things off for now, on the brink of war with China. Stay tuned!
submitted by Bubzoluck to SAR_Med_Chem [link] [comments]

2023.06.09 04:26 PrincessoftheDead Our Towns Big Dam Problem [Part 1]

Do you know how some decisions in life just feel so right? Imagine a nice warm pizza right out of the oven. The pizza is covered in gooey cheese, warm meats, and whatever else will delight the eyes and nose so late into the night. So image, if you will, going out for just the briefest of seconds to enjoy the crisp feel of the fall air on your face. You come back to the apartment building that you, and appropriately 50 or 60 of your neighbors call home, only to find smoke billowing down the halls as you suddenly remember that you turned on the burner, and not the oven to preheat, and the smoke is from that pizza you left on the stove. If you feel like burrowing down the deepest hole after reading that, just remember that you are not alone. In the last week, I have taken a job at a hydroelectric power station as an operator, which at the time felt like an easy no-brainer decision. The job description was nothing if not a little enticing. There was a hefty sign-on bonus, more money than even I thought I was worth, and housing courtesy of the Corps of Engineers, which consider the aforementioned fire above, I needed pretty badly. My name is Kate Fugate, I am 24, and in so, so much, debt that I have moved to a small town in the northern Appalachia wilderness hoping to carve out a life here. The town is very small, having a few local stores primary consisting of convenience stores, gas stations, and dollar stores. The town is deeply forested and has recently had the honor of having this vast area be designated a National park. The houses are sandwiched into a sharp valley, consisting of a river, sprawling train tracks, and speckled with bridges of all makes and builds. If you were to come here at night, and I very much doubt you would be here at night, you might also take notice of the emergency room-slash-post office combination with twinkling neon lights. If you plan on staying here for very long, and once again, I doubt it, you should get to know the staff. The main attraction, and the reason that I am christening this journal, is that as much as I would like to believe otherwise, this place is weird but we will get into that more a bit later. What should be the most prominent feature of the town, the dam, is actually not in town. It is about 15 miles upstream, hidden on an unmarked road nestled in a forgotten corner of the park. This fortress spans the length of the river from hill to hill, and is a huge concrete wall with an office building made of brick and a stunningly massive art -deco window spanning the two floors of this structure neatly tucked off the side like an after thought. There are massive, brilliant flood lights spanning the entire length of the dam and stretching pretty far upstream. The concept is pretty simple, water goes in, spins turbines, and comes out on the other side, and creates the miracles that we all know and love: electricity. In addition, this place prevents flooding and is an all-around great place for serving the town as an early indicator for fires and other disasters. To make matters even more excruciatingly boring and downright fucking frustrating is that there no cell or internet connections to the dam or the cabin nearby that I get to call home. The formal answer I got back for this pile of fake manure is that the cell tower determined the population to “insignificant” to put a cell tower in this area, which I can almost buy. The sorry excuse for the internet is that the park service determines this spot too high of a national security threat and doesn’t want the risk of Russians destroying the place or something, this reasoning being absolutely shit if you ask me. In order to still get a tiny shred of civilization, I have to climb a stairway to heaven itself up a fire tower, on a hill to get just enough Wi-Fi to keep some semblance of sanity. And let me tell you, my ass is burning, my tounge is dry, and my lungs are one iota from exploding from the effort, and it is worth it. My first day here started off with my coworker, Sam, showing up two hours late for our designated meeting. He was dressed in bright white pants and a striped plunging v-neck tiger shirt and I would be lying if I didn’t say my first impression was trying to find a camera crew, because I was just certain that someone was trolling with me. He was average height, approximately 35, black hair, blue eyes, and very well groomed hair, and huge muscular arms and, all-in-all, gave off an energy that he thought he was a very pretty boy. We shake hands, before he cocks his head and give me a quizzical look, “Hey I noticed on your paperwork, is your name actually —“ I cut him off hard and fast, “Yes, it is. My parents were a bit, well, downright eccentric, alright? Don’t use that name, don’t even remember it alright. Do me a favor and call me Kate, Katie if you prefer.” He looks a bit taken aback and I feel a shred of remorse for the hostility, “Can do, may name is Samuel Carrington but Sam sounds more approachable if you wouldn’t mind using that.” We take a quick tour of the facility going into the offices, him quickly pointing out the landlines, emergency switches, exits, ect. He goes over the more technical aspects of the job, but then stops right before going into the turbine room, looks me dead in the eye with more seriousness than I thought was possible. “There are only a handful of rules you absolutely must follow: 1. Treat the equipment well, it is fucking EXPENSIVE and a lot of it is specialized. There is no hydroectric repair store just sitting around the corner. 2. Do not leave the site. I am dead serious about this one. Do. Not. Leave. The. Site. The only time you can leave is if you have someone competent here. I am only here two days a week as I have other obligations with the government, as you know the rest is up to you until we can get more people here. 3. Don‘t turn off the turbines for any reason. There are people downstream that stake their lives on the continual operation of this place. 4. If, for whatever reason, this place can not operate due to exceptional circumstances, or can no longer contain the river you must activate the emergency system. In addition to letting out an alert, it allows for people to know in advance to get to higher ground. This is critical, we are the only thing preventing everyone downstream a brutal watery demise.“ We head continue the turbine room talk about more dull operating procedures and then stop by a small office space. Sam stops and swings open the door which reveals all of a tiny efficiency apartment. “This is my room while I am here, if you need anything feel free to swing by.” He gives me a wink as I contemplate vomiting on his stupid gold tasseled shoes “We have a cabin for you since no other apartments exist and it was left furnished by my last guy.” We walk a short gravel path uphill to a small old cabin with a porch. He swings open the door, leaving very little to the imagination. Bed and mattress, fridge, stove, fill nearly all the available space. Right smack in the middle of the table sits a pissed off mostly hairless cat, that jumps off the table gives us a hiss for good measure and runs off into the woods. “Look, we can probably get rid of that if you want. I have no clue how it got in here, or hey, look at it this way! You already have a built in roommate! Feel free to decorate this place anyway you want, if you want I can go get us some food, and I can help you move in. Tomorrow I can go on a grocery run.” I open the cabinet to find an assortment of canned oddities left over from the last occupant. “No, that really won’t be necessary, but thank you so much for the offer.” I say trying to be nice. And then the thought occurred to me that this guy is being perhaps a bit too friendly. “Hey, is it alright if I have some, umm, well, overnight friends over? Very special female friends?” I asked trying to be subtle to see if that would discourage him. “Well douse me in gasoline and toss me a match. Are you a lesbian? That is so freaking awesome! I love chicks too, how cool is that? I shoulda known what with the flannel and pickup truck.” He says, totally oblivious to my growing acceptance that this guy was mostly harmless, if not a touch stupid. Sam cracks open the fridge, and rapidly shuts it back, as a slightly warm pungent smell swaggers into the room. “Yeah, definitely gonna get some real groceries tomorrow.” “Yep, that’s me, I’m a super lesbian.” I lie feeling like this statement may come back and haunt me. I turn on the kitchen facet as black water spills out. Sam looks at it a little concerned, “Might want to let that run for a bit, if it doesn’t clear soon, I’ll look into having it fixed. But look, seriously, if you need any help at all, don’t hesitate to call. This place is pretty spooky and it is easy to get hurt or in trouble out here. I’ve only been here about 3 months and my last coworker got pretty messed up. I liked him pretty well and it is an easy, if not boring job but it can take a toll.” Sam stepped out on the porch shooting a slightly nervous look at the woods before looking back at me. I waved him out, “It is alright, I’m fine, I can take care of myself. I will see you bright and early in the morning.” Sam nodded at me with me with a warm smile and made the short trek back to the dam. Night swiftly fell, and I was clutching my stomach off loading the contents into the porcelain alter for a cruel sadistic god. I hadn’t checked the expiration date too closely before downing a can of beef tounge I had found in the cabinets, which in retrospect was such a fuckingly stupid move on my part. I stepped back into the main living area to see just a swift glint of metal, before listening to the “Crash” as my widow was busted in and a hand swiftly unlocked the door from the inside. “Shit, this is real bad.” My brain thought. As my body tensed for a fight, in walked a figure in a green ranger uniform. The guy was 26-27, 5’11, light brown hair, green eyes, fair skin. He looked absolutely furious but satisfied. “I got you now, you jackass arsonist.” He says, grabbed me by the arms and tossing me on a stuffed chair hard. I feel a flash of pain on my ass as I land. “Damn, I realllly hope that wasn’t a needle.” I think as jump back up. Now, he looked back at me with with sheer bewilderment in his eyes. “OH shit, oh shit, I am gonna die.” I feel dread sneak into me as I scramble looking around. I take up a knife from the counter and plunge it into his hand. He lets out a yelp and given me a kick to my already twisted stomach. ”This is it.” I think as I land on the ground, and take the chance to grab his leg while it is still in the air. I push forward as he stumbles backwards. “Wait, but your not -“ he tries to slide out of the cabin but I pull down his socks and bite like a rabid dog, with all the energy I had. I taste a glint of metal. He starts really letting his lungs work now before coming to his senses again and grabs a fire extinguisher off the porch and hits me squarely with it. My vision swiftly faded to white after that. My next memory has me coming back to consciousness in a hospital room. I am under a blanket with cows on it, and look over to see a shitty thin blue curtain with yellow ducks on it. As I try to piece back my memory, I hear a commotion on the other side of the curtain. One female voice nearly splitting my ears says, “Are you a dumbass? You look like one to me dumbass. You obviously weren’t thinking, dumbass. God, what a dumbass.” Another male voice joins in, ”A girl, you beat a harmless girl senseless. And the poor thing was starting the job at the power plant. If you weren’t in already in the hospital, I’d put here, but to be fair that would make Dr. Sanders work harder, and unlike you I actually like the guy.” An older man wearing a white coat comes in about this time who I presume is the aforementioned individual, gives me the mouth zipping motion, a wink and walks to the other side of the curtain. “Well, she’s dead. You may as well see your handiwork.” The old doctors says. A younger voice pipes up, “B-B-But it was an accident. I didn’t mean-“ The curtain flies open to reveal two police officers, a short and slightly heavy male and a tall African American woman. Both looking ready to kill the park ranger in bed with his hand bandaged up. The young man looks at me absolutely horrified. I can’t help but let out a small snicker at the scene. The white haired doctor cracks up at the look of pure indignation I shoot park ranger. “She’ll be fine.” He says. The two officers looked a bit more at ease. Dr. Sander then goes on to say after sitting down on the edge of my bed, “You spooked us just a bit there, that one over there” he points to the park ranger, “sprayed you down with a fire extinguisher and caused some temporary asphyxiation.” The guy piped up, “I am so so so sorry. My name is Reuben, call me Ben. I’m so sorry, I had you mistaken for someone else. I’ll make this up to you. I really really fucked this up. Please don’t hate me,” he says. He was genuine, I fully believed that. “Glad you said, that Ben, because I’m pretty sure I need a door now. My name is Katie.” I went over and gave him a light smack to the back of the head. Dr. Sanders gave a puzzled look and picked my chart off the bed, “Wait, isn’t your name -,”. I stopped him, “Yep, it is, please for the love of all that is holy, just don’t.” After that, the female officer who’s name I learned was Talia, dropped me back off at the dam the next morning. Sam who had only the vaguest of ideas of what had gone on that night was filled in by Talia of the rest of the details and she quickly leaves afterwards leaving a cloud trail in the gravel. “Well,” Sam says “I guess this means your leaving.” “Are you kidding?” I say, “I only just got here.” Sam cracks a wide smile, “You’re in luck then, I forgot to show you something yesterday.” We go into the dam, down into the basement under the water level under the turbine rooms. I gasp as I look into the room, it was beautiful. There was a massive window looking out underwater. I could swear for the slightest second though that a fish swam by, displaying three eyes, and a sharp row of teeth. I knew in that moment that this river holds terrible and dark secrets and I had not even dipped toe in them. This is Katie, signing off, until next time.
submitted by PrincessoftheDead to nosleep [link] [comments]

2023.06.09 03:52 comradebeastball AE -> SDR Manager Salary Negotiation

I’ve been in sales for about 15 years starting at a B2C boiler room selling low ticket ($200-400 deal size) for 2 years.
Started a similar company and ran the sales floor training outbound lead gens, similar to an SDR and 1099 closers.
Moved into tech as an SDR 3 years ago and after 1.5 years moved to SDR manager for 6 months.
I wanted closing experience so I moved companies to a startup working smb/mm.
It had been about 2 years and I’m looking for something different. I’ve wanted to enter management and I like the company I’m at and a position for SDR manager had opened that I’ve interviewed for.
I’m pretty certain I’ll get the offer but there are still commissions due over the next 12 months from my time as an AE. I would also like a higher base than they have alluded to in the internal job posting.
If I get the offer, what’s the best way to go about negotiating some of the future commission I would have earned as an AE as well as the higher base?
For context, I’d be managing a team of 10 and I would be the 4th SDR manager at the company. The salary posted is $85k with a $40k variable with the potential to hit accelerators bring the top OTE to $165k. I’d like to ask for $100k base with the expectation of getting $90k base and 6 months of reoccurring commissions from my role as AE.
Thoughts on how to handle this or if I should be asking for more?
submitted by comradebeastball to salesdevelopment [link] [comments]

2023.06.09 03:45 bestongrouppyrolysis Features Of A Continuous Pyrolysis Plant

Features Of A Continuous Pyrolysis Plant
When you are a budding entrepreneur and considering choosing a new clients, why not purchase a pyrolysis plant. A pyrolysis plant utilizes its namesake technology to transform waste tires, plastic and a whole lot of other products into useful products which you can use in a variety of industries. As an example, pyrolysis of waste tires can produce fuel oil, carbon black, steel wire plus some other products. Similarly, pyrolysis of plastic can also yield several useful products. It is a wonderful way to build a solid business and assist the environment. After all, you will certainly be processing waste matter which is of no use to anyone.
When you start researching Beston continuous pyrolysis plant for sale, you will see that there are various types of plants but in the following paragraphs, we are going to discuss the advantages of buying a continuous pyrolysis plant. One of the leading benefits of a continuous plant is these plants are fully automated and because the name suggests, can be operated continuously. These are far more efficient and you could operate those round the clock and these could be operated straight, with no issues, for over 30 days. To put it briefly, you only have to keep offering the raw material necessary for processing and then there won't be any problems.
On the flip side, you would need to clean the plant and perform certain other operations to maintain using a batch plant. This is the reason, a continuous plant is more efficient and contains a much higher processing capacity when compared with a batch plant.
Another necessary component that differentiates good quality plants from others may be the yield obtained through pyrolysis. Well-designed continuous plants are designed for providing a much higher yield in comparison with other sorts of plants. Simply speaking, you may expect a continuous plant to create a lot more fuel oil as compared to a batch plant which should help in strengthening your financial well being. The sole potential bottleneck in this particular process is definitely the accessibility of raw material.
While these are one of the major features of a continuous pyrolysis plant, it does not always mean that you can buy any plant and expect it to supply great outcomes. A good deal is determined by the complete design of the plant and the grade of components used in the plant. If your plant hasn't been designed well, it won't be capable of make efficient usage of heat energy generated inside the pyrolysis chamber which will bring about higher fuel consumption minimizing yield. Similarly, some plant designs should not be employed in countries with stricter environmental regulations. Also, some plants have a much higher cost and never make any kind of financial sense. In short, you will need to do further research to find a model that works well with your requirements. Contact the pyrolysis reactor manufacturers.
To conclude, a continuous type pyrolysis plant offers a variety of advantages as compared with a batch type plant. However, you need to research several models and discover something that is definitely appropriate for your particular situation.
submitted by bestongrouppyrolysis to u/bestongrouppyrolysis [link] [comments]

2023.06.09 03:37 richi-carmen Regular maintenance of the biomass pellet mill

Regular maintenance of the biomass pellet mill
What are the benefits of normal maintenance of the biomass pellet mill and biomass pellet machine production line? In fact, clinical and efficient upkeep approaches can make the biomass pellet assembly line kept up excellent quality, consequently boosting the outcome. It only takes some time for upkeep to attain unforeseeable outcomes. Why not do it?
A great set of biomass pellet mill needs to cooperate with scientific upkeep work in order to allow it to run with high performance and also barrier-free for a long period of time, so as to keep the efficiency of the tools and extend the service life of the biomass pellet tools, so regarding better develop even more earnings.
So exactly how should the biomass pellet production line be kept? The scientific technique needs to be to keep it once a month as well as a major upkeep every 6 months. The upkeep and upkeep of the biomass pellet mill is very essential, and also this essential link can not be neglected.
The general maintenance of the biomass pellet mill does not require to pay much money. Usually, it is simply simple oil injection, the firmness of the bolts, as well as the adjustment of the space. Upkeep triggers damage to the devices.
RICHI Machinery is a commercial group generally focused on the biomass pellet mill offer for sale, as well as also covers a few other strategic businesses such as animal feed equipment, natural plant food pellet machine, components and elements and so on. Richi Machinery will certainly give all customers with in-depth maintenance treatments for the biomass pellet production line, and also our after-sales personnel will certainly educate the consumer's staff, to make sure that consumers have no worries.
Related post: bamboo pellet machine
The upkeep of the biomass pellet mill concentrates on long-term stability as well as unremitting efforts. It might not see any kind of effect in a short time, but after a long-lasting comparison, it will certainly be located that the impact of this upkeep and also no maintenance is completely different.
So now those buddies who are making use of the biomass pellet mill, take a little time to do a regular upkeep, which is beneficial to the biomass pellet assembly line as well as your very own earnings.
RICHI Equipment biomass pellet mill offer for sale, has covered more than 109 nations and also regions all over the world from 1995, items are exported to the Middle East, South America, Africa, Southeast Asia as well as premium markets such as Europe and the United States.
If you wish to know more regarding warm sell good quality biomass pellet mill available for sale Australia, factory straight supplied 2 load per hour biomass pellet mill to buy Indonesia, automation lubrication system biomass pellet mill to buy Malaysia, high performance small capability biomass pellet mill for sale Thailand, expert style biomass rubber pellet mill to buy Netherlands, please get in touch with Richi Machinery for details.
1. Knowledge of biomass pellet machining pellet gas.
How high is the calorific worth of biomass briquette gas after biomass pellet machining? What are the attributes? What is the extent of application? Allow's have a look with the biomass pellet mill supplier.
( 1) Features of biomass fuel:.
Green power is tidy and also environmentally friendly:.
The combustion is smokeless, odor free, tidy and eco-friendly. Its sulfur content, ash web content, and nitrogen material are much less than those of coal, oil, and so on, and also no carbon dioxide exhausts. It is an environmentally friendly as well as tidy power and delights in the credibility of " eco-friendly coal".
Affordable and also high included value:.
The price of use is a lot lower than that of oil power. It is a tidy power that replaces oil strongly supported by the state, as well as has a broad market room.
The thickness increases as well as the storage space and transport are convenient:.
The formed fuel by biomass pellet mill is little in quantity, big in particular gravity as well as high in density, which is convenient for handling, conversion, storage space, transportation and also continual use.
High effectiveness and power conserving:.
High calorific value, 2.5 ~ 3 kg of wood pellet fuel calorific value amounts 1 kg of diesel calorific value, however the cost is less than half of diesel, and also the fatigue price can reach greater than 98%.
Wide application and also solid applicability:.
The pellet gas made by biomass pellet mill can be widely used in industrial and agricultural production, power generation, heating, central heating boiler heating, food preparation, and also it is suitable for system families.
( 2) Application extent of biomass fuel:.
Instead of traditional diesel, hefty oil, natural gas, coal and also other petrochemical energy sources, it can be utilized as fuel for thermal power tools such as central heating boilers, drying equipment, and also home heating heaters. The pellets made from timber resources have a reduced calorific value of 4300 ~ 4500 kcal/kg.
( 3) What is the calorific worth of biomass gas pellets?
For example:.
all kinds of yearn (Korean yearn, white yearn, sycamore pine, fir, etc), difficult miscellaneous timber (oak, catalpa, elm, etc) is 4300 kcal/kg;.
Soft assorted timber (poplar, birch, fir, and so on) is 4000 kcal/kg.
The low calorific value of straw pellets is 3000 ~ 3500 kcal/kg.
Bean stalk, cotton stalk, peanut covering, and so on 3600 kcal/kg;.
Corn stalk, rape stalk, and so on 3300 kcal/kg;.
Wheat straw is 3200 kcal/kg;.
Potato straw is 3100 kcal/kg;.
Rice straw is 3000 kcal/kg.
Related post: bagasse pellet mill
2. Biomass pellet mill is "carbon neutral tool".
The EU is the first area on the planet to commit to low-carbon development. It has reached its carbon optimal as well as is relocating in the direction of carbon nonpartisanship. Its experience is worth picking up from.
The EU's GDP accounts for 22.54% of the globe's overall, power usage make up 8%, and also carbon emissions account for 8.79% in the very same period. To achieve carbon neutrality in the power system, biomass-based renewable energy is used instead of fossil power.
Judging from the general power structure of the 27 EU countries, biomass power make up 65% of renewable energy; from the point of view of carbon emission decrease, biomass power represent 43%, rating initially.
The factor: Biomass energy made by biomass pellet mill is chemical power and also the only eco-friendly fuel that can be stored as well as moved. Dealing with diversified and also multi-period heating demands, biomass gas from the biofuel pellet equipment can be flexibly completely satisfied, and biomass resources are abundant as well as distributed. It is extensively used as well as affordable, and also it is more affordable than fossil power for heating. As an example, Denmark, Sweden, and Finland in north Europe have developed a affordable biomass energy sector chain based on a wide variety of farming as well as forestry wastes, and have actually become the biggest proportion of the energy market.
Biomass energy made by biomass pellet mill works with existing fossil energy infrastructure. For example, the six 660MW coal-fired systems of Drax, the biggest coal-fired nuclear power plant in the UK, are all converted to biomass to accomplish no carbon exhausts and also acquire substantial carbon emission decrease advantages; biomass energy is the only renewable energy selection that can totally replace fossil energy. It can not just meet the needs of the three significant energy terminals, power, electricity and heat, but additionally produce bio-based products to replace petroleum-based materials, which can not be attained by other renewable energy sources.
3. Development Fad of Biomass Gas Pellet Market.
( 1) Recently, the number of pellet cpus buying biomass pellet mill has raised.
( 2) The biomass pellet mill has actually kept a quick growth trend, and also there should be a large market space in the future. Collecting pertinent details, we discovered that from 2010 to 2013, the ordinary yearly sales of biomass pellet equipments increased from 228 million yuan to 1.985 billion yuan. Ships in all parts of the country, gradually creating an commercial chain advantage.

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2023.06.09 03:35 sarecycling Tyre Pyrolysis Plant On The Market

Tyre Pyrolysis Plant On The Market
Are you looking for an exceptional quality tyre pyrolysis plant available for purchase? Then, you will be in the right spot. Choosing a waste tire pyrolysis plant has numerous advantages. Tire pyrolysis is a chemical procedure that recycles waste tires at high temperatures inside an oxygen-free environment. You will definately get valuable byproducts including fuel oil, carbon black, steel wire, and combustible gas due to the pyrolysis process. These byproducts are very popular from the industrial sector. The truly amazing profit is the biggest reason why people prefer to buy tire pyrolysis plants available for purchase. Here are some of the most critical facts to consider when looking for the best tire pyrolysis plant available for sale.
Waste tires are getting to be a large problem around the world. Usually, waste tires fill the landfills across the country that will create environmental hazards. Waste tires take a huge selection of years to decompose fully. It affects the ecosystem and fosters numerous problems for life on earth. For this reason tire pyrolysis is recognized as one of the best types of earning a handsome profit while preserving environmental surroundings as well.

Investing in a tire pyrolysis plant is no small decision. Tire pyrolysis plants are costly, and factors to consider to complete the homework before purchasing a quality plant with a reasonable price. There are lots of considerations when purchasing a tire pyrolysis plant. Deciding on a reliable manufacturer or supplier is the most important thing. Actually, you will find a host of equipment manufacturing companies across the world. But a Chinese manufacturer will always provide a quality plant at a reasonable cost. China is the most popular destination when it comes to investing in tire pyrolysis plants at affordable costs. The best thing about using the services of Chinese manufacturers is that you may contact them online without having to check out the country. The most recent technology makes it much simpler to locate pyrolysis plants on the web and negotiate the sale. The present Chinese manufacturers have professional websites and employ fluent English-speaking staff to handle foreign buyers.

Upon having researched an effective manufacturer in China or other part of the world, the next step is to discover the quality of the pyrolysis reactor - which is the main part of the plant. The quality of the reactor is directly connected to the service lifetime of the full plant. The content, welding, and the thickness in the reactor are essential considerations when deciding the grade of the pyrolysis reactor. Reliable manufacturers make use of a 16mm Q245R boilerplate to create the pyrolysis reactor. This boilerplate will ensure the reactor could withstand the specified high-temperature heating. Also, the pyrolysis reactor must be welded using auto-welding technology with three-step welding to assure the grade of the plant. It prevents cracks in the plant during long-time operations. These are the most critical aspects to consider when you are interested in the ideal tyre pyrolysis plant available for sale available on the market.
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2023.06.09 02:40 Shayan_Shiva What is the best application of physics in everyday life?

🌌⚙️🔬Physics, as the fundamental science that explores the nature of matter and energy, finds practical applications in numerous aspects of our everyday lives. Here are some examples of how physics enhances our daily experiences:

1️⃣ Electricity and Electronics: Understanding the principles of electricity and electronics is essential for operating devices like smartphones, computers, televisions, and household appliances. Physics helps us comprehend concepts such as voltage, current, resistance, and circuits, enabling us to harness and utilize electrical energy safely and efficiently.

2️⃣ Transportation: Physics plays a crucial role in various forms of transportation. The principles of mechanics, such as Newton's laws of motion, are applied in designing vehicles like cars, bicycles, and airplanes. Understanding concepts like friction, aerodynamics, and energy conversion allows us to optimize fuel efficiency, enhance safety, and improve the overall performance of transportation systems.

3️⃣ Medical Imaging: Physics enables medical advancements, particularly in the field of medical imaging. Techniques like X-rays, computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound rely on the principles of radiation, wave behavior, and electromagnetic interactions. These technologies aid in the diagnosis, treatment planning, and monitoring of various medical conditions.

4️⃣ Energy Generation: Physics provides the foundation for generating and harnessing different forms of energy. From the principles of thermodynamics in power plants to the conversion of solar energy in photovoltaic cells, understanding the behavior of energy allows us to develop sustainable and efficient energy sources. Physics contributes to the development of renewable energy technologies, such as wind turbines and solar panels, which are crucial in addressing global energy challenges.

5️⃣ Optics and Communication: Optics, the study of light and its properties, plays a vital role in various communication systems. Physics helps us understand phenomena like reflection, refraction, and diffraction, which are essential for the design of optical fibers, lenses, and laser technologies. This knowledge forms the basis of modern telecommunications, including fiber-optic communication, lasers, and digital displays.

6️⃣ Structural Engineering: Physics guides the design and construction of structures, ensuring their stability and safety. Concepts like forces, equilibrium, and material properties enable engineers to calculate the loads that structures can withstand, leading to the construction of bridges, buildings, and infrastructure that can endure environmental conditions and maintain structural integrity.

🌌⚙️🔬 These examples highlight just a few of the numerous ways in which physics enhances our everyday lives. From the technology we use to the way we move and communicate, physics provides the scientific understanding necessary for innovation, problem-solving, and improving our quality of life.

🔍💡 By embracing and applying the principles of physics, we can continue to unlock new possibilities, address global challenges, and advance scientific knowledge, fostering a better future for humanity.

#PhysicsInEverydayLife #PracticalApplications #ScientificUnderstanding #EnhancingOurWorld #babieblue #shaynly
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2023.06.09 02:34 OmegaXDOOMX Recovery Boiler Furnace Light Protection

I work as an operator on a chemical recovery boiler in a pulp mill. Every so often i have to attend to the furnace by going to clean my liquor nozzles and inspect the bed in the furnace to ensure it's running properly and whatever. All fine and dandy. Nothing out of the ordinary.
There are a couple of old-timers that have worked here for decades. One has catarax. Others have vision issues. However, there are a few that have these Didymium Glasses that they swear by for when they look into the furnace. Apparently they filter out certain wavelengths of light and make looking into the furnace easier and overall safer considering the obvious UV and IR protection. The certain light filters essentially let you look straight through the flames and get a good, clean look at the char bed. And before anyone asks, yes there is a furnace camera, but its in a less than stellar spot to begin with and only shows about 25% of the furnace.
I've looked around online and these things are NOT cheap. Some pairs are like 400 bucks canadian. I know i could use tinted safety glasses instead, but lighting around the boiler is low as it is and they wouldnt let me see deeper into the furnace.
What are you guys using, if anything, to look into yoir furnaces? Anyone else have any luck with these rare earth glasses? Lookimg for options and opinions before i buy them because i dont want to get permanent eye damage over time. I plan to be in a job like this for like 30+ years. It'll catch up with me lol.
submitted by OmegaXDOOMX to powerengineering [link] [comments]

2023.06.09 02:06 2th Travis Gafford: "Multiple sources have informed me that the @NALCSPA and @lolesports have reached an agreement, ensuring the LCS will return for Summer Split"
Multiple sources have informed me that the @NALCSPA and @lolesports have reached an agreement, ensuring the LCS will return for Summer Spliit.
An official announcement is expected within the next hour.
Update: Announcement made. LCS returns June 14.
Following a two-week delay, the LCS will move forward with a reformatted Summer Split regular season that will take place over 6 weeks starting on June 14. LCS matches this Summer will now be played on Wednesdays, Thursdays, and Fridays starting at 2:00 PM PT / 5:00 PM ET at the Riot Games Arena.
Updated information on Summer Split, including tickets and revised match schedule, will be available on Friday, June 9 at 9:00 AM PT / 12:00 PM ET on
“Delaying Summer Split was not a decision we took lightly, but ultimately the dialogue between the league, the LCSPA, and teams provided the space to realign on shared goals for the future of the LCS and NACL. Building for the long-term sustainability and success of the LCS ecosystem is the win-condition for us all,” said Naz Aletaha, Global Head of LoL Esports. “We want to thank the LCS fans, players, and teams for their patience during this period and look forward to seeing players back on the LCS stage next week.”
The LCS, the LCSPA, and a team representative chosen by the 10 LCS organizations have met regularly during this period. Throughout these discussions, the group engaged in dialogue across a wide range of topics for both LCS and NACL players. Based on what is financially scalable and sustainable for the ecosystem, league, and teams, the discussions resulted in the following:
  • A new NACL business model, in addition to the previously committed $300,000, that shares revenue between the tournament operator and participating teams to drive towards long-term sustainability
  • Improvements to the NACL governance model, including a Team Participating Agreement (TPA) and vetting process of the participating team organizations
  • Minimum 30-day notice and severance requirement for players earning up to 1.5 times the league minimum salary and minimum two-week termination notice for non-resident LCS players (players and teams are free to negotiate terms over-and-above this)
  • Creation of a working group between teams and the LCSPA to better optimize scrim schedules
  • Reinforcement of healthcare insurance requirements for international LCS players when they arrive in the U.S.
  • Refinement of working procedures between the LCS, LCSPA, and teams to continue conversations around the improvement of the competitive landscape in North America
“The LCS Summer Split kicks off Wednesday and we’ll build toward the Final at the Prudential Center in August and Worlds this fall,” said Raúl Fernandez, Senior Director, Esports, Americas. “We are committed to bringing the best of League to the NA community and will be continuing to evolve the LCS with that goal in mind.”
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2023.06.09 01:48 Califanoal CleanTech Stocks Highlights the Top 10 Reasons to Invest in Sage Potash Corp (SAGE.v)

CleanTech Stocks Highlights the Top 10 Reasons to Invest in Sage Potash Corp (SAGE.v)
The US has an annual demand for potash of over 9 million tons, while domestic production is less than 500,000 tons, making the country dependent on global sources like Canada, Russia, and Belarus.
CleanTech Stocks recently featured Sage Potash Corp (Ticker: SAGE.v) as an investment opportunity that combines both securing the future of US potash production and financial returns.
Read here:
The article highlights that Sage has made a significant potash find in the US with its Sage Plain Potash Project. It also lists the top 10 reasons to invest in Sage Potash including the company's market cap, lower capital expenditure, demand for potash, low shipping costs, project resource and economic estimate, environmental practices, comparables, and more.
Although Sage currently has a market cap of $13 million, the in-situ value of their inferred potash resource, based on current pricing, is over $18 billion. Sage Potash is a newly listed small-cap company, but it has a clear path to production. Comparatively, the only current US producer, Intrepid Potash, has a market cap of $265 million, while global giants like Nutrien and SQM have market caps between $18-30 billion.
With drill permits already in process, Sage Potash expects to have their initial pilot plant operating within 12 months. They have plans for rapid expansion and can utilize debt financing for much of the expansion.
Perhaps most importantly, the company has a possible catalyst incoming as it is set to release its PEA in the coming weeks. This will also provide investors with an in-depth analysis of the mine's economics.
Make sure to check out the article for more information. Posted on behalf of Sage Potash Corp.
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Wyoming Governor Signs Bill in Support of Rare Earth Industry
Rare Element Resources Ltd. (the “Company” or “RER”) (OTCQB: REEMF) is pleased to announce the completion of the funding agreement for the previously announced $4.4 million grant from the Wyoming Energy Authority (the “WEA”). The WEA grant is a cost reimbursement award for future expenditures related to construction of the Company’s rare earth processing and separation demonstration plant to be located in Upton, Wyoming. The plant is also supported by the U.S. Department of Energy (the “DOE”) through a previously announced $21.9 million financial award. The funding provided through the DOE and WEA programs is expected to cover more than half of the estimated project costs.
In further support of the rare earth industry in Wyoming, earlier this year, Governor Mark Gordon signed a bill into law to advance the process for Wyoming to assume certain licensing and regulatory aspects of the rare earth industry. The unanimously approved bill seeks to amend the existing agreement state status between the state and the U.S. Nuclear Regulatory Commission (the “NRC”) to allow Wyoming the permitting and regulatory authority related to rare earth element source materials. Once approved by the NRC, Wyoming will have primacy for the NRC’s licensing of Wyoming-based rare earth processing facilities.
“We are very pleased with the many affirmative steps that the state of Wyoming is taking in support of the rare earth industry and the Company. The Bear Lodge Project has one of the highest-grade rare earth deposits in North America, and its location positions Wyoming to be a key player in developing a domestic rare earth supply chain,” Brent Berg, President and CEO of RER, stated. “Construction of the demonstration plant is the next step in advancing the Company’s innovative recovery and separation technology, developed with our world-class technology partner, General Atomics. The plant will provide data critical for the design of a commercial facility. The state’s legislative initiative will have licensing efficiency benefits for commercial-scale rare earth operations. We applaud Wyoming’s forward thinking and goal of economic diversification and appreciate its ongoing support of the rare earth industry and the Company.”
The rare earth processing and separation demonstration plant project, led by General Atomics, has completed the final design and is progressing licensing and permitting, with the final significant license expected this summer. Procurement of equipment has been underway for the last several months. The total 40-month timeline, which commenced in October 2021, includes commencement of construction in the second half of 2023 with operations expected to start in mid-2024.
“Rare earth elements are of the utmost importance to our country’s energy security and something we must continue to advance in order to achieve equal footing in this global market,” said Rob Creager, Executive Director of the Wyoming Energy Authority. “Wyoming has an opportunity to be a leader in providing these critical resources to our country. We are committed to the continued support of projects like these that will propel not only our own communities but our entire nation forward.”
The demonstration plant will utilize the Company’s proprietary recovery and separation technology and is expected to produce high-purity neodymium/praseodymium (Nd/Pr) oxide that is key in producing high-strength permanent magnets. These magnets are the driving technology in numerous defense, medical and green technologies, including the manufacture of electric vehicles and wind turbines. Data generated from the demonstration plant will be used in the design and completion of an economic evaluation for a full-size commercial plant and Bear Lodge Project, as well as validate the cost and environmental benefits of the process over traditional recovery methods.
Rare Element Resources Ltd. is a publicly traded, strategic materials company focused on delivering rare earth products for technology, energy, and defense applications by advancing the Bear Lodge Critical Rare Earth Project in northeast Wyoming. Bear Lodge is a significant mineralized district containing many of the less common, more valuable, critical rare earths that are essential for high-strength permanent magnets, electronics, fiber optics, laser systems for medical technology and defense, as well as technologies like electric vehicles, solar panels, and wind turbines.
General Atomics is a privately held company engaged in the development and production of advanced technology products and systems for the energy and defense sectors. Rare Element Resources’ majority shareholder, Synchron, is an affiliate of General Atomics.
Wyoming Energy Authority advances Wyoming’s energy strategy by driving data, technology, and infrastructure investments. Focusing on an “all-of-the-above” energy mix, the WEA’s strategy includes products from legacy industries, along with the newer players advancing renewable energy and opportunities in hydrogen, advanced nuclear, geothermal, and rare earth elements. The WEA was created in 2020 by the Wyoming State Legislature by merging the Wyoming Infrastructure Authority and the Wyoming Pipeline Authority.
Forward-Looking Statements
This news release contains forward-looking statements within the meaning of securities legislation in the United States and forward-looking information within the meaning of securities legislation in Canada (collectively, “forward-looking statements”). Except for statements of historical fact, certain information contained herein constitutes forward-looking statements. Forward-looking statements are usually identified by our use of certain terminology, including “will,” “believes,” “may,” “expects,” “should,” “seeks,” “anticipates,” “plans,” “has potential to,” or “intends” (including negative and grammatical variations thereof), or by discussions of strategy or intentions. Such forward-looking statements include statements regarding the rare earth processing and separation demonstration plant, the estimated costs of the plant, the plans and timing for the design, licensing, construction, and operation of the plant, the plant’s expected utilization of the Company’s proprietary technology, the licensing of Wyoming-based rare earth processing facilities, and the Company’s ability to realize the grant funding. Factors that could cause actual results to differ materially from those contemplated, expressed or implied by the forward-looking statements contained in this news release include, but are not limited to, the ability to obtain demonstration plant licensing and permits, inflation and supply chain issues, ability to meet the requirements of the WEA grant funding and timing of the funding, and other matters discussed under the caption “Risk Factors” in our Annual Report on Form 10-K for the fiscal year ended December 31, 2022, and our other periodic and current reports filed with the U.S. Securities and Exchange Commission (the “SEC”) and available on and with the Canadian securities commissions available on

View source version on
Rare Element Resources :
Please contact Brent Berg at +1 720-278-2460 or [[email protected]](mailto:[email protected]) , for additional information.
Wyoming Energy Authority :
Please contact Honora Kerr at +1 970-270-1014 or [[email protected]](mailto:[email protected]) , for additional information.
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